Inside The absence of the enzyme, as in Crigler-Najjar syndrome type I, the amounts of unconjugated bilirubin will increase, resulting in jaundice. Unconjugated bilirubin is drinking water-insoluble, and high ranges can deposit within the brain bringing about a ailment named kernicterus. Extreme hyperbilirubinemia normally develops in the main few times https://www.youtube.com/shorts/IuPMi7CvqAo