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Timing of whole genome duplication is associated with tumor-specific MHC-II depletion in serous ovarian cancer

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Abstract Whole genome duplication is frequently observed in cancer. and its prevalence in our prior analysis of end-stage. homologous recombination deficient high grade serous ovarian cancer (almost 80% of samples) supports the notion that whole genome duplication provides a fitness advantage under the selection pressure of therapy. Here. https://foldlyers.shop/product-category/trimmer/
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